On one question, at least, critics and readers of Sinclair Lewis's works are likely to agree—Arrowsmith is his greatest novel. In it the first American to win the Nobel Prize for Literature has created a gallery of characters which, it is safe to predict," will remain unforgettable for generations. Leora, the indomitable comrade and wife; Gottlieb, the incorruptible scientist; Sondelius, the crusader against plagues; and Arrowsmith, the doctor in whom a holy flame is kindled—these are characters who give to the novel its immense power and its blazing indignation.